Treating Wernicke-Korsakoff Syndrome

Grant number: 1011141 | Funding period: 2011 - 2017

Completed

Abstract

Wernicke-Korsakoff syndrome is a common and frequently undiagnosed neurological disease due to thiamine deficiency. The condition leads to cognitive and neurological disability and mostly affects people with alcohol dependence. Wernicke-Korsakoff syndrome is eminently treatable with thiamine, although we have insufficient knowledge regarding the best dose of thiamine to treat the condition. This project proposes two controlled trials to evaluate treatment effectiveness of thiamine for Wernicke-Korsakoff syndrome.

Related publications (3)

Over a Century of Study and Still Misunderstood: Recognizing the Spectrum of Acute and Chronic Wernicke–Korsakoff Syndrome

SJ Scalzo, SC Bowden

2023-11-01

The aim of this study was to objectively evaluate the hypothesis that the neuropsychological presentation of Korsakoff’s syndrome,..

Alcohol related dementia and Wernicke-Korsakoff Syndrome.

SC bowden, S scalzo

2017-02-24

Many of these specialists find it hard to keep up to date in all aspects of dementia. This book helps solve that problem. The new ..

Wernicke-Korsakoff syndrome not related to alcohol use: A systematic review

SJ Scalzo, SC Bowden, ML Ambrose, G Whelan, MJ Cook

2015-12-01

Objective: Although Wernicke-Korsakoff syndrome (WKS) is a common condition, diagnosis remains difficult. WKS not associated with ..

University of Melbourne Researchers

Stephen Bowden